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 If you like exercise, you will have less breast cancer Relationship between exercise and breast cancer risk found by overseas research analyzing data of 130,000 people

October is Breast Cancer Prevention Month, and it's time to raise awareness about breast cancer. It is now believed that daily lifestyle habits are important for cancer prevention, including breast cancer. This time, in an overseas study, an analysis based on data from 130,000 women was conducted, and it was shown that being active (exercising) is associated with the risk of breast cancer. It seems that the risk is reduced by about 40%. What actions will reduce breast cancer? Woman Breast cancer is also increasing in Japan. In 2018, 93,858 people were diagnosed annually, making it the most common cancer among women. Lifestyles that lead to its prevention are attracting interest. This time, a research group of the Breast Cancer Association Consortium (BCAC), an international organization that is studying the relationship between breast cancer and genes, used characteristics called "single nucleotide We investigated whether being active was associated with breast cancer risk by a method called Mendelian randomization. A person's genetic characteristics are closely related to their lifestyle. Therefore , information about whether a person is active or not is obtained from genetic characteristics, and attempts are made to elucidate whether that information is related to the risk of breast cancer. It is a method that is attracting worldwide attention as an analysis that applies the fact that when genetically predicted, there is a high probability that a person will adopt the lifestyle that is actually predicted. The research group used the UK Biobank, a British database that collects genetic and health information from about 500,000 people, to determine how much exercise they do, how long they spend exercising vigorously, and how long they spend sitting. We examined the genes that lead to the trait. On top of that, information on genetic characteristics, genetic information of more than 130,000 European women (approximately 75,000 women who developed breast cancer), characteristics of whether they are active or not, and whether or not they developed breast cancer. They matched the information and calculated how being active or not was associated with breast cancer risk. Women's data were examined by grouping by premenopausal or postmenopausal status, breast cancer type (eg, triple-negative or hormone receptor-positive), stage, and grade.

Any type or stage of breast cancer

Woman

It turns out that being active definitely seems to be linked to a lower risk of breast cancer. Specifically, they calculated that a 41% lower risk of developing breast cancer was associated with an overall higher level of genetically-informed predicted activity (i.e., a natural propensity to exercise). rice field. The results were similar whether menopausal or not, or whether breast